Affron®: The Natural Choice for Mood, Stress, and Sleep Balance

Affron® is a premium saffron ingredient backed by 9 human clinical studies that have shown to improve mood in healthy consumers with occasional stress and anxiety, and to improve sleeplessness.

The following main mechanisms of action of Affron® have been identified:

- Inhibition of the reuptake mechanism of dopamine, norepinephrine, and serotonin, increasing the concentrations of these neurotransmitters in the synaptic cleft of neurons, thereby improving mood balance.- Antioxidant effect against the excessive oxidative stress produced during occasional anxiety or stress processes in the central nervous system*.- Anti-inflammatory action in stressed neural tissue, decreasing hippocampal levels of apoptotic biomarkers and stress signal molecules*.