Alpha Arbutin - Personal Care Ingredient

Alpha-arbutin:
CAS No.: 84380-01-8
Specification: ≥99.5%
α-arbutin is a new type of hydroquinone glucoside with an α-glucosyl bond.
Arbutin is commercially used as a skin-whitening agent in cosmetic industry. It works by competitive inhibition of the enzyme, tyrosinase, a key enzyme in the synthesis of melanin. Depending on the spatial structure of the glycosidic linkage between glucose and hydroquinone, arbutin forms two epimers: Alpha Arbutin and Beta arbutin.
Alpha Arbutin is enzymatically synthesized from hydroquinone and saccharides through transglycosylation reaction. Various carbohydrate-active enzymes such as α-amylase, α-glucosidase, transglucosidase, sucrose phosphorylase, and dextransucrase have been employed to synthesize Alpha Arbutin. It is one of the most advanced skin lightening ingredients on the market.