AOP cell efficacy tests catalogue

Product description

CELL EFFICACY:
antioxidant mechanism of action with four antioxidant cell-based assays addressing different mode of action; intracellular antioxidant activity providing quantitative antioxidant index, dose-response curve and efficacy concentrations allowing for ranking or comparison with standard antioxidants; intestinal absorption and bioavailability with an intestinal barrier model;- anti-inflammatory effect or immunomodulatory effect

Specifications

Categories	Lab service & equipment

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AOP booklet

Anti Oxidant Power (AOP) is a French biotech created in 2017 specialized in in vitro cell-based tests to demonstrate the efficacy of natural extracts, ingredients or finished products. We offer our solid expertise in cellular biology, antioxidants studies and cell redox homeostasis...

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AOP1

ANTIOXIDANT ACTIVITY : measure of intracellular ROS/ free radical scavenging activity. It provides antioxidant index, dose-response curve and efficacy concentrations allowing for ranking or comparison with standard antioxidants.

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AOP2

ANTIOXIDANT ACTIVITY: measure of the Nrf2 -regulated ARE pathway induction on hepatocytes. (ARE stands for Antioxidant Response Element, a genetic sequence which leads to enhanced expression of genes coding for antioxidant proteins and which can be activated in response to oxid...

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AOP3

ANTIOXIDANT ACTIVITY: measure of ROS/free radicals scavenging activity at the cell plasma membrane (AAPH/DCFH-DA assay).

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AOPCAT

ANTIOXIDANT ACTIVITY: Measure of catalase-like activity or hydrogen peroxide neutralization.

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AOP TRANS

INTESTINAL ABSORPTION: measure of intestinal barrier integrity with trans epithelial electrical resistance (TEER). Evaluation of intestinal absorption or trans epithelial transport. Evaluation of bioactivity by collecting the basolateral fractions from the in vitro intestinal cell monolayer for antioxidant...

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