Casperome®

CASPEROME™ is a purified mixture of triterpenoid acids from the gum resin of Boswellia serrata. Given the poor bioavailability of these compounds, Indena has formulated the extract with Phytosome technology to optimize their absorption. BOSWELLIA extracts have been demonstrated to be effective in the management of various inflammatory response functions including those that occur in the bowel, joints, bones, respiratory airways and in the brain, with a mechanism of action that involves the modulation of the natural inflammatory response both acting on prostanoid synthesis (mPGE2S) and protein degradation (caspases), and transcription factors (Nf-κB). Boswellic acids such as 11-keto-β boswellic (KBA) and its acetylated counterpart (AKBA), have been proposed as selective 5-lipoxygenase inhibitor and than capable to manage the inflammatory response function through leukotriene inhibition. The bioavailability of boswellic acids from CASPEROME™ is greatly optimized both at the plasma and at the tissue level. Boswellia extracts have been demonstrated to be useful for bowel related inflammatory responses and to improve physical function in subjects with joint challenges through significant improvements in the articular cartilage status. RECOMMENDED USE AND DOSE: CASPEROME™ is a yellow powder and may be utilized in a variety of supplement formulations.